Course Description:USP General Chapter <645> Water Conductivity is the primary method for determining inorganic/ionic impurities in Purified Water and Water for Injection (WFI), and has been adopted by multiple pharmacopoeias. USP <645> Water Conductivity is one of the two primary chemical limit tests (USP <643> Total Organic Carbon is the other) to determine that there is sufficient control/reduction of chemicals in the water purification system. In addition, electrical conductivity is also used as an analytical on-line, real-time process control tool for the entire water purification process and other manufacturing processes. This course will explain the purpose of this test, instrumentation and calibration requirements, on-line and off-line measurements, temperature compensation, and test limit requirements for various pharmaceutical waters.Objectives:
- Understand the basic principles of conductivity.
- Determine instrumentation and temperature compensation requirements.
- Understand the differences between on- and off-line measurements of pharmaceutical waters.
- Understand the test limits for the different stages of testing for various bulk and sterile waters for USP and other pharmacopoeia.
- Review USP <1644> Theory and Practice of Electrical Conductivity Measurements of Solutions.
Who should participate:
- Analytical chemists
- QA/QC managers
- Compliance managers
- Water system engineers and owners
- Lab managers
- Production managers
- Regulatory affairs specialists
Access Duration:Access to this course expires 6 months from the date of registration or until you mark the course ‘Complete’ – whichever occurs first.